MRK-740

  • Chemical Properties
CAS No. 2387510-80-5 Cat. No. BCP40609
Name MRK-740
Synonyms MRK 740; MRK740;
Formula C25H32N6O3 M. Wt 464.56
  • Biological Activity
Description MRK-740 is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor. It is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4.
Pathways Epigenetics 
Targets Histone Methyltransferase 

Structure

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