JHU37152
| CAS No. | 2369979-67-7 | Cat. No. | BCP40725 |
| Name | JHU37152 | ||
| Synonyms | JHU-37152;JHU 37152;DREADD ligand; | ||
| Formula | C19H20ClFN4 | M. Wt | 358.8 |
| Description | JHU37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mAChR | ||
Structure
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