BMS-346567
CAS No. | 953807-31-3 | Cat. No. | BCP41192 |
Name | BMS-346567 | ||
Synonyms | BMS346567; BMS 346567; | ||
Formula | C33H42N4O5S | M. Wt | 606.78 |
Description | BMS-346567 is apotent and selective dual angiotensin II and endothelin A receptor antagonist. BMS-346567 demonstrated superiority over irbesartan (an AT(1) receptor antagonist) in the normal SHR model of hypertension in a dose-dependent manner, demonstrating the synergy of AT(1) and ET(A) receptor blockade in a single molecule. | ||
Pathways | GPCR/G Protein | ||
Targets | Angiotensin Receptor |
Structure
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