BMS-346567

  • Chemical Properties
CAS No. 953807-31-3 Cat. No. BCP41192
Name BMS-346567
Synonyms BMS346567; BMS 346567;
Formula C33H42N4O5S M. Wt 606.78
  • Biological Activity
Description BMS-346567 is apotent and selective dual angiotensin II and endothelin A receptor antagonist. BMS-346567 demonstrated superiority over irbesartan (an AT(1) receptor antagonist) in the normal SHR model of hypertension in a dose-dependent manner, demonstrating the synergy of AT(1) and ET(A) receptor blockade in a single molecule.
Pathways GPCR/G Protein 
Targets Angiotensin Receptor 

Structure

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