AZD-5305
CAS No. | 2589531-76-8 | Cat. No. | BCP41765 |
Name | AZD-5305 | ||
Synonyms | AZD5305;AZD 5305; | ||
Formula | C22H26N6O2 | M. Wt | 406.48 |
Description | AZD5305 is a potent and oral active, second-generation PARP (highly selective PARP1) inhibitor. AZD5305 showed highly effective and sustained anti-tumor activity in selected BRCAm xenograft and PDX in vivo models. At the same time, AZD5305 also showed benefits when used in combination with chemotherapy. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | PARP |
Structure
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