AZD-5305

  • Chemical Properties
CAS No. 2589531-76-8 Cat. No. BCP41765
Name AZD-5305
Synonyms AZD5305;AZD 5305;
Formula C22H26N6O2 M. Wt 406.48
  • Biological Activity
Description AZD5305 is a potent and oral active, second-generation PARP (highly selective PARP1) inhibitor. AZD5305 showed highly effective and sustained anti-tumor activity in selected BRCAm xenograft and PDX in vivo models. At the same time, AZD5305 also showed benefits when used in combination with chemotherapy.
Pathways Cell Cycle/DNA Damage 
Targets PARP 

Structure

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