(R)-Camptothecin

  • Chemical Properties
CAS No. 110351-92-3 Cat. No. BCP41819
Name (R)-Camptothecin
Synonyms 20R-Camptothecin;(R)-(-)-Camptothecin;
Formula C20H16N2O4 M. Wt 348.35
  • Biological Activity
Description (R)-(-)-Camptothecin is an alkaloid that has been used for the treatment of cancer. (R)-(-)-Camptothecin binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.

Structure

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