AZ Dyrk1B 33
| CAS No. | 1679330-37-0 | Cat. No. | BCP41848 |
| Name | AZ Dyrk1B 33 | ||
| Synonyms | AZ-Dyrk1B-33; | ||
| Formula | C19H16N4 | M. Wt | 300.36 |
| Description | AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 value of 7 nM. It shows better selectivity than AZ 191 and shows no off-target effects against a panel of 124 kinases tested. It displays distinct cellular effects when compared to DYRK1B knockdown through siRNA and has been demonstrated cellular in vitro activity. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | DYRK | ||
Structure
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