Norleual
CAS No. | 334994-34-2 | Cat. No. | BCP41927 |
Name | Norleual | ||
Synonyms | L-Phenylalanine,L-norleucyl-L-tyrosyl-L-leucyl-y(CH2-NH)-L-histidyl-L-prolyl-; | ||
Formula | C41H58N8O7 | M. Wt | 774.95 |
Description | Norleual is an angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | c Met |
Structure
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