PPT
CAS号 | 263717-53-9 | 货号 | BCP41931 |
中文名 | PPT | ||
英文名 | PPT | ||
中文别名 | |||
英文别名 | Propyl pyrazole triol; | ||
分子式 | C24H22N2O3 | 分子量 | 386.44 |
生物活性 | PPT, also known as Propyl pyrazole triol, is an ERα selective agonist with a 410-fold relative binding affinity for ERα (49%) versus ERβ (0.12%) and therefore activates gene transcription only through ERα. PPT significantly decreased infarct size in an in vivo rabbit model of ischemia-reperfusion injury. PPT also exerts anti-diabetic effects in mouse models. | ||
信号通路 | Hormone Pathay | ||
靶 点 | Estrogen Receptor |
结构式
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