TPX-0131
| CAS No. | 2648641-36-3 | Cat. No. | BCP42131 |
| Name | TPX-0131 | ||
| Synonyms | TPX0131;TPX 0131; | ||
| Formula | C21H20F3N5O3 | M. Wt | 447.41 |
| Description | TPX-0131 is a CNS-penetrant, next-generation ALK inhibitor that has potency against wild-type ALK and a spectrum of acquired resistance mutations, especially the G1202R solvent front mutation and compound mutations, for which there are currently no effective therapies. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | ALK | ||
Structure
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