科利维林
| CAS号 | 867021-83-8 | 货号 | BCP42673 |
| 中文名 | 科利维林 | ||
| 英文名 | Colivelin | ||
| 中文别名 | |||
| 英文别名 | H-SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-OH; H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-; | ||
| 分子式 | C119H206N32O35 | 分子量 | 2645.10 |
| 生物活性 | Colivelin is a brain penetrant neuroprotective peptide and a potent activator of STAT3, suppresses neuronal death by activating STAT3 in vitro. Colivelin exhibits long-term beneficial effects against neurotoxicity, Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease. Colivelin has the potential for the treatment of alzheimer's disease and ischemic brain injury | ||
| 信号通路 | Neuro Signaling Pathway Wnt/Stem Cell | ||
| 靶 点 | Amyloid β Stat | ||
结构式
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