Ac-FLTD-CMK
| CAS No. | 2376255-48-8 | Cat. No. | BCP43135 |
| Name | Ac-FLTD-CMK | ||
| Synonyms | |||
| Formula | C26H37ClN4O8 | M. Wt | 569.05 |
| Description | Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3. | ||
| Pathways | Protease/Metabolic Enzyme Apoptosis Pathway | ||
| Targets | Caspase | ||
Structure
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