Cilofexor tromethamine
| CAS No. | 2253764-93-9 | Cat. No. | BCP43200 |
| Name | Cilofexor tromethamine | ||
| Synonyms | GS-9674 tromethamine salt;GS-9674 tromethamine; | ||
| Formula | C32H33Cl3N4O8 | M. Wt | 707.99 |
| Description | Cilofexor is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | FXR | ||
Structure
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