CC-90010
| CAS No. | 1706738-98-8 | Cat. No. | BCP43205 |
| Name | CC-90010 | ||
| Synonyms | Trotabresib; CC 90010; CC90010; | ||
| Formula | C21H21NO4S | M. Wt | 383.46 |
| Description | CC-90010 is a potent and orally active BET inhibitor. CC-90010 preferentially binds to the second bromodomain (BD2) of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histones. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of proliferation in BET-overexpressing tumor cells. | ||
| Pathways | Epigenetics | ||
| Targets | Epigenetic Reader Domain | ||
Structure
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