Bisindolylmaleimide IV
| CAS No. | 119139-23-0 | Cat. No. | BCP43512 |
| Name | Bisindolylmaleimide IV | ||
| Synonyms | Arcyriarubin A; | ||
| Formula | C20H13N3O2 | M. Wt | 327.34 |
| Description | Bisindolylmaleimide IV is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM. | ||
| Pathways | TGF beta/Smad Epigenetics | ||
| Targets | PKC | ||
Structure
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