ICCB-19 HCl
| CAS No. | 1803605-68-6 | Cat. No. | BCP43518 |
| Name | ICCB-19 HCl | ||
| Synonyms | ICCB-19 hydrochloride;ICCB 19 HCl;ICCB19 HCl; | ||
| Formula | C12H22ClN3OS | M. Wt | 291.84 |
| Description | ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | RIP | ||
Structure
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