ONC206
| CAS No. | 1638178-87-6 | Cat. No. | BCP43713 |
| Name | ONC206 | ||
| Synonyms | ONC-206; ONC 206; | ||
| Formula | C23H22F2N4O | M. Wt | 408.44 |
| Description | ONC206 is a chemical analogue of ONC201. ONC206 is a benzyl-flurobenzyl imipridone that has highly potent activity in preclinical models of difficult-to-treat neuroendocrine tumors and sarcomas. ONC206 acts as a selective antagonist of DRD2 at nanomolar concentrations and has broad-spectrum anti-tumor activity. ONC206 may address tumor types where the properties of ONC201 do not permit for complete therapeutic engagement in vivo. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | Dopamine Receptor | ||
Structure
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