PF-05231023
| CAS No. | 1037589-69-7 | Cat. No. | BCP43801 |
| Name | PF-05231023 | ||
| Synonyms | Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD;PF05231023; PF 05231023; PF-5231023; PF5231023; PF 5231023; | ||
| Formula | C26H32N4O8 | M. Wt | 528.55 |
| Description | PF-05231023 is an FGF21-receptor agonist, it is also a potential treatment for T2DM. PF-05231023 suppresses oxidative-stress-induced inflammation in photoreceptors. PF-05231023 decreases the variability of retinal NRF2 levels and displays a trend (non-significant) towards increased NRF2 levels in Akita mice. PF-05231023 (10 mg/kg; i.p.) reduces retinal inflammation in diabetic mice. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FGFR | ||
Structure
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