TPX-0046
CAS No. | TPX0046 | Cat. No. | BCP43814 |
Name | TPX-0046 | ||
Synonyms | TPX0046;TPX 0046; | ||
Formula | C21H21FN6O3 | M. Wt | 424.43 |
Description | TPX-0046 is a novel RET/SRC inhibitor with a mean IC50 of 17 nM for RETG810R in Ba/F3 cell proliferation assay.TPX-0046 is a structurally differentiated RET inhibitor that is potent against a range of RET fusions and mutations including SFMs. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | Src/Bcr Abl RET |
Structure
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