BIT225
| CAS号 | 917909-71-8 | 货号 | BCP43946 |
| 中文名 | BIT225 | ||
| 英文名 | BIT225 | ||
| 中文别名 | |||
| 英文别名 | BIT-225;BIT 225; | ||
| 分子式 | C16H15N5O | 分子量 | 293.32 |
| 生物活性 | BIT225, a novel acyl-guanidine, is a novel antiviral drug that blocks Vpu ion channel activity and has anti-HIV-1 activity in vitro. The antiviral effect of BIT225 is most pronounced in cells of the myeloid lineage. With infected circulating monocytes and tissue-resident macrophages representing a key cellular reservoir of HIV-1, BIT225 has a potential role in the eradication of the virus from the host. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | HIV | ||
结构式
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