Cl-amidine TFA

化学数据

CAS号	1043444-18-3	货号	BCP43968
中文名	Cl-amidine TFA
英文名	Cl-amidine TFA
中文别名
英文别名	Cl-Amidine (trifluoroacetate salt);Cl-amidine TFA;
分子式	C14H19ClN4O2.C2HF3O2	分子量	424.81

用途

生物活性	Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity.

生物活性

Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity.

结构式

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