TL-895
| CAS No. | 1415823-49-2 | Cat. No. | BCP44090 |
| Name | TL-895 | ||
| Synonyms | TL895;TL 895; | ||
| Formula | C25H26FN5O2 | M. Wt | 447.5 |
| Description | TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1.5 nM and 11.9 nM, respectively. TL-895 is used be for JAKi-relapsed/refractory myelofibrosis, acute myeloid leukemia, COVID-19 and cancer research. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | BTK | ||
Structure
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