BAY 85-8501

  • Chemical Properties
CAS No. 1161921-82-9 Cat. No. BCP44126
Name BAY 85-8501
Synonyms BAY85-8501; BAY-85-8501; BAY 858501; BAY858501; BAY-858501;
Formula C22H17F3N4O3S M. Wt 474.46
  • Biological Activity
Description BAY 85-8501 is a new, highly potent and selective neutrophil elastase inhibitor (IC50 for HNE = 0.065 nM, LipE = 7.2). BAY 85-8501 has shown in vivo efficacy in various preclinical animal models. BAY 85-8501 is currently being tested in clinical studies for the treatment of pulmonary diseases.
Pathways Protease/Metabolic Enzyme 
Targets Elastase 

Structure

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