D-DOPA
| CAS号 | 5796-17-8 | 货号 | BCP44158 |
| 中文名 | D-DOPA | ||
| 英文名 | D-DOPA | ||
| 中文别名 | |||
| 英文别名 | |||
| 分子式 | C9H11NO4 | 分子量 | 197.19 |
| 生物活性 | D-DOPA is the dextrorotary isomer of the dopamine precursor L-DOPA. It can be converted to L-DOPA via sequential oxidation and transamination, which are mediated by D-amino acid oxidase and DOPA transaminase, respectively, in rat kidney homogenates. It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner. Intraventricular administration of D-DOPA increases striatal dopamine levels in rats. D-DOPA induces contralateral turns in a rat model of Parkinson's disease induced by 6-OHDA. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Dopamine Receptor | ||
结构式
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