盐酸左旋沙丁胺醇
| CAS号 | 50293-90-8 | 货号 | BCP44201 |
| 中文名 | 盐酸左旋沙丁胺醇 | ||
| 英文名 | Levalbuterol hydrochloride | ||
| 中文别名 | |||
| 英文别名 | Levalbuterol HCl;R-albuterol hydrochloride; | ||
| 分子式 | C13H22ClNO3 | 分子量 | 275.77 |
| 生物活性 | Levalbuterol Hydrochloride is the hydrochloride salt form of levalbuterol, a relatively selective sympathomimetic beta-2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol hydrochloride binds to beta-2 adrenergic receptors in bronchial smooth muscle and activates intracellular adenyl cyclase, thereby increasing the production of cyclic-3', 5'-adenosine monophosphate (cAMP). Increased cAMP levels lead to the activation of protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation of bronchial smooth muscles. The increased cyclic AMP concentrations also inhibit the release of inflammatory mediators from mast cells. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Adrenergic Receptor | ||
结构式
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