KDM2A/7A-IN-1
CAS No. | 2169272-46-0 | Cat. No. | BCP44938 |
Name | KDM2A/7A-IN-1 | ||
Synonyms | |||
Formula | C33H38N4O | M. Wt | 506.68 |
Description | KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16 μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases. | ||
Pathways | Epigenetics | ||
Targets | Histone Demethylase |
Structure
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