KDM2A/7A-IN-1

  • Chemical Properties
CAS No. 2169272-46-0 Cat. No. BCP44938
Name KDM2A/7A-IN-1
Synonyms
Formula C33H38N4O M. Wt 506.68
  • Biological Activity
Description KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16 μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases.
Pathways Epigenetics 
Targets Histone Demethylase 

Structure

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