LY255283
CAS No. | 117690-79-6 | Cat. No. | BCP45104 |
Name | LY255283 | ||
Synonyms | LY-255283;LY 255283; | ||
Formula | C19H28N4O3 | M. Wt | 360.45 |
Description | LY 255283 is a selective, competitive antagonist of BLT2 receptors (IC50 values are ~ 1 and > 10 μM at human recombinant BLT2 and BLT1 receptors respectively). Inhibits LTB4-induced contraction of lung parenchyma (pA2 = 7.2), and reduces LTB4-mediated airway obstruction in guinea pigs following i.v. and oral administration.. | ||
Pathways | GPCR/G Protein | ||
Targets | Leukotriene Receptor |
Structure
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