FLT3-IN-3

  • Chemical Properties
CAS No. 2229050-90-0 Cat. No. BCP45355
Name FLT3-IN-3
Synonyms FLT3-IN3; FLT3-IN 3; SAN50900; SAN-50900; SAN 50900;
Formula C27H38N8O M. Wt 490.64
  • Biological Activity
Description FLT3-IN-3 is a potent and selective FLT3 inhibitor. SAN50900 displays nanomolar activity in biochem. assays and selectively blocks proliferation of AML cell lines harboring FLT3-​ITD mutations, whereas other transformed and normal human cells are several orders of magnitude less sensitive.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets FLT3 

Structure

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