特考韦瑞
| CAS号 | 869572-92-9 | 货号 | BCP46174 |
| 中文名 | 特考韦瑞 | ||
| 英文名 | Tecovirimat | ||
| 中文别名 | |||
| 英文别名 | SIGA-246; SIGA246; SIGA 246; ST-246; ST 246; ST246; | ||
| 分子式 | C19H15F3N2O3 | 分子量 | 376.33 |
| 生物活性 | Tecovirimat, also known as SIGA-246 and ST-246, is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection. Tecovirimat is a novel antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus-induced disease tested to date. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Cytochrome P450 | ||
结构式
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