CJ033466
CAS No. | 519148-48-2 | Cat. No. | BCP46275 |
Name | CJ033466 | ||
Synonyms | CJ-033466; CJ 033466; | ||
Formula | C19H28ClN5O | M. Wt | 377.91 |
Description | CJ-033466 is a potent and selective 5-HT4 partial agonist (EC50= 0.927 nM). Displays > 1000-fold selectivity for 5-HT4 over other 5-HT and D2 receptors. Exhibits gastroprokinetic effects in vivo following oral administration. Weakly blocks hERG (IC50 = 2.6 μM). | ||
Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
Targets | 5 HT Receptor/Serotonin Receptor |
Structure
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