CJ033466

  • Chemical Properties
CAS No. 519148-48-2 Cat. No. BCP46275
Name CJ033466
Synonyms CJ-033466; CJ 033466;
Formula C19H28ClN5O M. Wt 377.91
  • Biological Activity
Description CJ-033466 is a potent and selective 5-HT4 partial agonist (EC50= 0.927 nM). Displays > 1000-fold selectivity for 5-HT4 over other 5-HT and D2 receptors. Exhibits gastroprokinetic effects in vivo following oral administration. Weakly blocks hERG (IC50 = 2.6 μM).
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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