SC-1

  • Chemical Properties
CAS No. 1313019-65-6 Cat. No. BCP46435
Name SC-1
Synonyms Stat3-IN-7;SC1;SC 1;
Formula C21H13ClF3N3O2 M. Wt 431.8
  • Biological Activity
Description SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines.
Pathways Jak/Stat Pathway Wnt/Stem Cell 
Targets Stat 

Structure

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