Paprotrain
| CAS No. | 57046-73-8 | Cat. No. | BCP46472 |
| Name | Paprotrain | ||
| Synonyms | |||
| Formula | C16H11N3 | M. Wt | 245.28 |
| Description | Paprotrain is a reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (Ki = 3.4 μM). Inhibits the basal ATPase activity of MKLP-2 (IC50 = 1.35 μM). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Kinesin | ||
Structure
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