花生五烯酸
| CAS号 | 10417-94-4 | 货号 | BCP46769 |
| 中文名 | 花生五烯酸 | ||
| 英文名 | Icosapent | ||
| 中文别名 | 二十碳五烯酸; | ||
| 英文别名 | Eicosapentaenoic acid;Timnodonic acid;Icosapentaenoic acid; | ||
| 分子式 | C20H30O2 | 分子量 | 302.45 |
| 生物活性 | Icosapent is the free fatty acid (FFA) form of eicosapentaenoic acid (EPA), a polyunsaturated long-chain fatty acid found in fish oil with a 20-carbon backbone and 5 double bonds, with potential supplementing, anti-inflammatory, anti-thrombotic, immunomodulating, anti-angiogenic and chemopreventive activities. Upon administration of icosapent, the free form of EPA is incorporated in cell membrane phospholipids and replaces arachidonic acid. This inhibits arachidonic acid conversion into thromboxanes and prostaglandin E2 (PGE2). Upon oral administration of icosapent, the EPA-FFA prevents and suppresses colonic neoplasia and reduces polyp formation and growth through as of yet not fully elucidated mechanisms. | ||
| 信号通路 | Epigenetics | ||
| 靶 点 | Histone Demethylase | ||
结构式
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