TGFβRI-IN-3
CAS No. | 2763602-67-9 | Cat. No. | BCP46788 |
Name | TGFβRI-IN-3 | ||
Synonyms | |||
Formula | C28H23N3O2S | M. Wt | 465.57 |
Description | TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology. | ||
Pathways | TGF beta/Smad | ||
Targets | TGF β/Smad |
Structure
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