ALLO-2

  • Chemical Properties
CAS No. 1357350-60-7 Cat. No. BCP46892
Name ALLO-2
Synonyms Smo inhibitor ALLO-2;ALLO2;ALLO 2;
Formula C18H12F3N5O M. Wt 371.32
  • Biological Activity
Description ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
Pathways GPCR/G Protein 
Targets Smoothened/Smo 

Structure

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