安西奈德
| CAS号 | 51022-69-6 | 货号 | BCP47048 |
| 中文名 | 安西奈德 | ||
| 英文名 | Amcinonide | ||
| 中文别名 | |||
| 英文别名 | CL-34699;CL34699;CL 34699;Cyclocort; Amcinonidum; Visderm; Amcinonida; Amcinonido; | ||
| 分子式 | C28H35FO7 | 分子量 | 502.57 |
| 生物活性 | Amcinonide is a synthetic glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, and immunosuppressive activity of the natural glucocorticoids. Amcinonide interacts with specific corticosteroid receptors and was internalized, which leads to binding of DNA and modification of gene expression. This results in synthesis of anti-inflammatory mediators while inhibiting synthesis of inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are achieved. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Glucocorticoid Receptor | ||
结构式
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