PDK4-IN-1 hydrochloride

  • Chemical Properties
CAS No. 2310262-11-2 Cat. No. BCP47278
Name PDK4-IN-1 hydrochloride
Synonyms PDK4 IN 1 hydrochloride; PDK4 IN-1 hydrochloride; PDK4-IN-1 HCl;
Formula C22H20ClN3O2 M. Wt 393.87
  • Biological Activity
Description PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity.

Structure

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