Umibecestat HCl
| CAS号 | 2365306-62-1 | 货号 | BCP48028 |
| 中文名 | Umibecestat HCl | ||
| 英文名 | Umibecestat HCl | ||
| 中文别名 | |||
| 英文别名 | Umibecestat hydrochloride; | ||
| 分子式 | C19H16Cl2F7N5O2 | 分子量 | 550.26 |
| 生物活性 | Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. CNP520 reduced brain and cerebrospinal fluid (CSF) Aβ in rats and dogs, and Aβ plaque deposition in APP-transgenic mice. CNP520 reduces Aβ load and neuroinflammation in APP‐transgenic mice. | ||
| 信号通路 | Neuro Signaling Pathway | ||
| 靶 点 | Beta secretase | ||
结构式
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