环二腺苷酸二钠盐
CAS号 | 2734909-87-4 | 货号 | BCP48318 |
中文名 | 环二腺苷酸二钠盐 | ||
英文名 | c-di-AMP disodium | ||
中文别名 | |||
英文别名 | Cyclic diadenylate disodium; Cyclic-di-AMP disodium; | ||
分子式 | C20H22N10Na2O12P2 | 分子量 | 702.38 |
生物活性 | c-di-AMP sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses. | ||
上下游产品 | 54447-84-6(环二腺苷酸) | ||
信号通路 | Others Pathway | ||
靶 点 | STING |
结构式
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