Snail/HDAC-IN-1
| CAS号 | 2415281-52-4 | 货号 | BCP48514 |
| 中文名 | Snail/HDAC-IN-1 | ||
| 英文名 | Snail/HDAC-IN-1 | ||
| 中文别名 | |||
| 英文别名 | CYD19; | ||
| 分子式 | C24H21FN8OS | 分子量 | 488.54 |
| 生物活性 | Snail/HDAC-IN-1 is a potent Snail/HDAC dual target inhibitor. Snail/HDAC-IN-1 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM and potent inhibition against Snail with a Kd of 0.18 μM. Snail/HDAC-IN-1 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis. | ||
| 信号通路 | Cell Cycle/DNA Damage Epigenetics | ||
| 靶 点 | HDAC | ||
结构式
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