AZD-5672
| CAS No. | 780750-65-4 | Cat. No. | BCP48543 |
| Name | AZD-5672 | ||
| Synonyms | AZD 5672; AZD5672; | ||
| Formula | C32H38F2N2O5S2 | M. Wt | 632.78 |
| Description | AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). AZD-5672 shows moderate activity against the hERG ion channel (binding IC50=7.3 μM). AZD5672 is a substrate of human P-gp, and inhibits P-gp-mediated digoxin transport (IC50=32 μM). AZD-5672 can be used for the research of rheumatoid arthritis. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | Potassium Channel P glycoprotein CCR | ||
Structure
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