Izuforant
| CAS No. | 1429374-83-3 | Cat. No. | BCP48744 |
| Name | Izuforant | ||
| Synonyms | JW1601;JW 1601;JW-1601; | ||
| Formula | C12H12BrN7 | M. Wt | 334.17 |
| Description | Izuforant (JW1601) is an orally active histamine H4 receptor (H4R) antagonist with an IC50 of 36 nM against human H4R. Izuforant also shows binding affinity of human serotonin 3 receptor (h5-HT3R) with an IC50 of 9.1 μM. Izuforant exhibits strong anti-pruritic and anti-inflammatory efficacies. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | Histamine Receptor | ||
Structure
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