(E/Z)-GSK-3β inhibitor 1

  • Chemical Properties
CAS No. 3367-88-2 Cat. No. BCP48909
Name (E/Z)-GSK-3β inhibitor 1
Synonyms (E/Z)-GSK-3inhibitor 1;(E/Z)-GSK-3|A inhibitor 1;
Formula C14H10N2O M. Wt 222.25
  • Biological Activity
Description (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM.
Pathways Wnt/Stem Cell PI3K/Akt/mTOR 
Targets GSK3 

Structure

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