Pitstop2
| CAS No. | 1332879-52-3 | Cat. No. | BCP48928 |
| Name | Pitstop2 | ||
| Synonyms | Clathrin-IN-1;Pitstop 2; | ||
| Formula | C20H13BrN2O3S2 | M. Wt | 473.36 |
| Description | Pitstop2 is a selective clathrin-mediated endocytosis (CME) inhibitor. Clathrin-IN-1 selectively inhibits amphiphysin association of clathrin terminal domain (TD) with an IC50 value of 12 μM. Clathrin-IN-1 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling. | ||
| Pathways | Protease/Metabolic Enzyme Microbiology/Virology | ||
| Targets | HIV Protease HIV | ||
Structure
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