Furosemide sodium

  • Chemical Properties
CAS No. 41733-55-5 Cat. No. BCP48937
Name Furosemide sodium
Synonyms Sodium furosemide;
Formula C12H12ClN2NaO5S M. Wt 354.74
  • Biological Activity
Description Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway 
Targets GABA Receptor NKCC 

Structure

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