L-733060 hydrochloride
| CAS号 | 148687-76-7 | 货号 | BCP49092 |
| 中文名 | L-733060 hydrochloride | ||
| 英文名 | L-733060 hydrochloride | ||
| 中文别名 | |||
| 英文别名 | L-733,060; L733,060; L 733,060; L-733060; L733060; L 733060; L-733060 HCl salt; | ||
| 分子式 | C20H20ClF6NO | 分子量 | 439.82 |
| 生物活性 | L-733,060 is an orally active, non-peptide, selective antagonist for the NK1 receptor, binding with a Ki of 0.08nM. L-733,060 has antidepressant and anxiolytic effects in animal studies, and reduces both the dopamine release and neurotoxicity produced by methamphetamine and cocaine. It shows antiinflammatory and anti-hepatotoxic effects in animals, and counteracts the development of hyperalgesia following nerve injury.[15][16] It also has anticancer effects in a variety of in vitro models. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | NK Receptor | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！