Filgotinib maleate
CAS No. | 1802998-75-9 | Cat. No. | BCP49095 |
Name | Filgotinib maleate | ||
Synonyms | GS 6034 maleate; GS6034 maleate; GS-6034 maleate; | ||
Formula | C25H27N5O7S | M. Wt | 541.58 |
Description | Filgotinib (maleate) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Filgotinib (maleate) can be used for rheumatoid arthritis (RA) and Crohn's disease research. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
Targets | JAK |
Structure
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