Exarafenib
  • 化学数据
CAS号 2639957-39-2 货号 BCP49200
中文名 Exarafenib
英文名 Exarafenib
中文别名
英文别名 RAF/KIN_2787; KIN-2787; KIN 2787; KIN2787;
分子式 C26H34F3N5O3 分子量 521.58
  • 用途
生物活性 Exarafenib is an orally available inhibitor of class I, II, and III B-Raf (BRAF) protein kinases, with potential antineoplastic activity. Upon administration, exarafenib binds to and inhibits Class I, Class II, or Class III B-Raf mutations. This prevents B-Raf-mediated signal transduction pathways, which may lead to an inhibition of tumor growth in B-Raf mutant cells. B-Raf protein kinases play a key role in the RAF/MEK/ERK signaling pathway, which is often deregulated and mutated in human cancers, and plays a key role in tumor cell proliferation and survival.
信号通路 MAPK Pathway 
靶 点 p38 MAPK Raf 

结构式

本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
全国免费电话：400-099-8200
在线客服:
技术支持:
orders@biochempartner.com
瀚香官网:
www.biochempartner.com
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！