Alintegimod
| CAS号 | 1378535-08-0 | 货号 | BCP49203 |
| 中文名 | Alintegimod | ||
| 英文名 | Alintegimod | ||
| 中文别名 | |||
| 英文别名 | 7HP349;7HP 349;7HP-349; | ||
| 分子式 | C28H32N2O6S4 | 分子量 | 620.81 |
| 生物活性 | 7HP349 is an oral therapy intended for use in combination with immunotherapy in order to improve the effectiveness of potentially any immunotherapeutic immune checkpoint inhibitors and infectious disease vaccines through a unique mechanism of action. It works as an allosteric activator of the integrins VLA-4 and LFA-1 which are essential elements that underlie rate-limiting steps in lymphocyte recruitment, extravascular trafficking, T cell activation and effector functions. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | Integrin | ||
结构式
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