Onilcamotide
CAS号 | 1164096-85-8 | 货号 | BCP49539 |
中文名 | Onilcamotide | ||
英文名 | Onilcamotide | ||
中文别名 | |||
英文别名 | RV001; | ||
分子式 | C96H177N39O24S | 分子量 | 2293.78 |
生物活性 | Onilcamotide is a cancer vaccine composed of an immunogenic peptide derived from the Ras homolog family member C (RhoC; Rho-related GTP-binding protein RhoC) that is emulsified in the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, onilcamotide may stimulate the host immune system to mount a humoral and cytotoxic T-lymphocyte (CTL) response against tumor cells expressing RhoC, which results in tumor cell lysis. RhoC, a tumor-associated antigen (TAA) that is overexpressed in a variety of tumor cell types, is associated with increased metastatic potential. | ||
信号通路 | Others Pathway | ||
靶 点 | Others |
结构式
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