Garsorasib
| CAS号 | 2559761-14-5 | 货号 | BCP49682 |
| 中文名 | Garsorasib | ||
| 英文名 | Garsorasib | ||
| 中文别名 | |||
| 英文别名 | |||
| 分子式 | C32H32F2N8O2 | 分子量 | 598.65 |
| 生物活性 | Garsorasib is an orally available inhibitor of the oncogenic KRAS substitution mutation, G12C, with potential antineoplastic activity. Upon oral administration, garsorasib selectively targets the KRAS G12C mutant and inhibits KRAS G12C mutant-dependent signaling. KRAS, a member of the RAS family of oncogenes, serves an important role in cell signaling, division and differentiation. Mutations of KRAS may induce constitutive signal transduction leading to tumor cell growth, proliferation, invasion, and metastasis. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Ras/Rho | ||
结构式
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